June 18, 2024

What are the uses of protease inhibitors?

Protease inhibitors have effects such as lowering blood pressure, anti-inflammatory, antiviral, delaying aging, and inhibiting tumor cell growth. Patients should use protease inhibitors under the guidance of a physician to ensure safe and effective medication.
DIFF ‘TailorCraft’ protease inhibitor screening system
1. Lowering blood pressure
Protease inhibitors lower blood pressure by reducing the activity of the renin angiotensin system. Protease inhibitors can be used to treat hypertension, such as captopril, enalapril, etc.
2. Anti inflammatory
Protease inhibitors can inhibit the production and release of inflammatory mediators, thereby exerting anti-inflammatory effects. Protease inhibitors can be used to treat various inflammatory diseases, such as nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen sodium.
3. Antivirus
Protease inhibitors can block key steps in virus replication, thereby inhibiting virus reproduction. Protease inhibitors are widely used in the development of antiviral drugs, such as acyclovir, lamivudine, etc.
4. Delaying aging
Protease inhibitors can slow down the rate of protein breakdown, preventing tissue damage and aging caused by excessive protein degradation. Protease inhibitors may have certain anti-aging effects and are used as additives in health products or cosmetics, such as licorice extract, soy isoflavones, etc.
5. Inhibiting tumor cell growth
Protease inhibitors can interfere with signaling pathways within cancer cells, inhibiting tumor cell proliferation and migration. Protease inhibitors are a strategy for tumor treatment, with clinical applications including targeted drugs such as gefitinib and erlotinib.
Protease inhibitors belong to broad-spectrum drugs, but should not be taken in large quantities for a long time. Pay attention to individual differences and possible side effects, such as indigestion, rash, etc. It is recommended to use them under the guidance of a doctor, especially for patients with a specific disease history or undergoing other treatments.